Cell Culture Media, Supplements, and Reagents
Gold Biotechnology Inc G-418 Sulfate 10 g
G-418 sulfate, also known as geneticin, is an aminoglycoside antibiotic similar in structure to gentamicin B1. It is commonly used in plant and mammalian cell culture as a selectable marker. It can be used to select for cells transformed with an iNOS promoter construct or neomycin resistance gene.
![Research Products International Corp Anisomycin from streptomyces griseolus [2-[(4-Methoxyphenyl)methyl]-3, 4-pyrrolidinediol-3-acetate], 10 Milligrams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-A50100-0.01.JPG-250.jpg)
Research Products International Corp Anisomycin from streptomyces griseolus [2-[(4-Methoxyphenyl)methyl]-3, 4-pyrrolidinediol-3-acetate], 10 Milligrams
Anisomycin is an antibiotic derived from Streptomyces griseolus. It inhibits protein synthesis in eukaryotic cells by blocking the peptidyl transferase activity of the 60S ribosomal subunit. This interference disrupts the elongation phase of protein synthesis, leading to the inhibition of new protein formation.
Anisomycin is widely used as a tool in cell biology and biochemistry to study cellular responses to stress, apoptosis, and various signaling pathways. Its ability to selectively inhibit protein synthesis allows researchers to investigate the role of specific proteins in cellular processes. Anisomycin induces cellular stress and activates various stress response pathways, making it valuable in studies focused on understanding how cells respond to environmental challenges.
Apexbio Technology LLC Anisomycin 22862-76-6 50mg
Anisomycin is an activator of c-Jun N-terminal kinase (JNK) a stress-activated protein kinase implicated in apoptotic signaling pathways regulating cell proliferation cell cycle progression and apoptosis It activates the JNK pathway at approximately 25 ng/ml concentration Experimental studies demonstrate anisomycin s capability to sensitize apoptosis-resistant cancer cell lines such as DU145 prostate carcinoma cells to Fas-mediated apoptosis as well as to induce apoptosis in leukemic HL-60 cells and primary mouse embryonic fibroblast cells by initiating JNK activation Anisomycin is thus widely utilized as a molecular tool in apoptosis-related research and insight into JNK-associated cell signaling
Medchemexpress LLC Lumefantrine-d9 | 2477594-24-2 | 97.0% | 1 MG
Lumefantrine-d9 is the deuterium-labeled version of Lumefantrine, an antimalarial drug. Lumefantrine is used in combination with Artemether, forming artemether-lumefantrine (AL), which serves as a first- and second-line antimalarial drug. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules as tracers for quantitation during drug development.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Apexbio Technology LLC Anidulafungin(Synonyms: Eraxis, Ecalta, LY303366, VER-002, Anidulafungin acetate, V-echinocandin, Vicuron echinocandin), 100mg, CAS: 166663-25-8.
Anidulafungin (CAS 166663-25-8) also known as LY-303366 is a semisynthetic derivative of echinocandin B exhibiting antifungal activity It acts by inhibiting fungal cell wall synthesis through interference with the enzyme -(1 3)-D-glucan synthase In vitro analyses demonstrate that Anidulafungin inhibits various Candida species including C albicans C glabrata C tropicalis and C parapsilosis (MIC90 0 08 0 32 0 32 5 12 g/ml respectively) as well as Aspergillus species (MIC90 0 02 g/ml) Lack of significant efficacy was shown against Cryptococcus neoformans and Blastomyces dermatitidis This compound is useful for research exploring antifungal resistance mechanisms and therapeutics
Enzo Life Sciences Antimycin A, (10mg), CAS Number: 1397-94-0
Antibiotic. Induces apoptosis, which is not prevented by the presence of Bcl-2. Inhibits mitochondrial electron transport specifically between cytochromes b and c1. Alternative Name: Antipiricullin, Virosin. CAS Number: 1397-94-0. MI: 14: 714 (A1) & 715 (A3). Appearance: White to faint yellow powder. Solubility: Soluble in 100% ethanol (50mg/ml). Long Term Storage: -20°C
Medchemexpress LLC Rifampicin (standard) | 13292-46-1 | MFCD00151389 | 95.5% | 822.94 g·mol⁻¹ | C43H58N4O12 | 10 MG
Rifampicin (standard) is an analytical reference standard of the antibiotic rifampicin intended for research and analytical applications. It is used for assay calibration, method validation, and as a reference in chromatographic and spectrometric analyses.
- Analytical reference standard for assay calibration and method validation.
- Suitable for chromatographic and spectrometric analysis.
- Reported purity 95.5%; see the certificate of analysis for batch-specific values.
- Available in small pack sizes for analytical workflows.
- Store under conditions recommended on the certificate of analysis.
eMolecules 80-77-3 | Chlormezanone | Combi-Blocks, Inc. | MFCD00143951 | 273.730 | C11H12ClNO3S | 98.000 | CN1C(c2ccc(Cl)cc2)S(=O)(=O)CCC1=O | 1g | 589788920
Chlormezanone | Combi-Blocks, Inc. | 80-77-3 | MFCD00143951 | 273.730 | C11H12ClNO3S | 98.000 | CN1C(c2ccc(Cl)cc2)S(=O)(=O)CCC1=O | 1g | 589788920
Medchemexpress LLC HY-100975 50mg Medchemexpress, TB5 CAS:948841-07-4 Purity:>98%
Medchemexpress, HY-100975 50mg TB5 CAS:948841-07-4 TB5 is a potent, selective and reversible inhibitor of hMAO-B with a Ki value of 0.11±0.01 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-10452 10mg Medchemexpress, Ixazomib citrate CAS:1239908-20-3 Purity:>98%
Medchemexpress, HY-10452 10mg Ixazomib citrate CAS:1239908-20-3 Ixazomib citrate (MLN9708) is a reversible inhibitor of the chymotrypsin-like proteolytic β5 site of the 20S proteasome with an IC50 of 3.4 nM and a Ki of 0.93 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Zd7288 | 133059-99-1 | MFCD00914937 | 99.8% | 292.81 g/mol | C15H21ClN4 | 100 MG
ZD7288 (ICI D7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker used as a research reagent to inhibit HCN-mediated currents in electrophysiology and pharmacology studies. Supplied as a high-purity solid for in vitro research; not for human or clinical use.
- Selective HCN channel blocker for in vitro electrophysiology.
- High purity (~99.8%) suitable for research applications.
- White to off-white solid form for convenient handling and storage.
- Molecular weight 292.81 g/mol; formula C15H21ClN4.
- Packaged as 100 MG for laboratory use.
- Storage: 4°C; in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Streptozotocin | 18883-66-4 | MFCD00006709 | ≥98% | 265.22 | 5 G
Streptozotocin (STZ) is an antibiotic commonly used in experimental animal models to induce diabetes. It enters B cells via the glucose transporter (GLUT2) and causes DNA alkylation, leading to the apoptosis of β cells. This compound is suitable for constructing models of both type 1 and type 2 diabetes.
- Induces cytotoxicity, oxidative stress, and mitochondrial dysfunction in HepG2 cells.
- Specifically transported by GLUT2 in GLUT2-expressing cells.
- Highly water-soluble and often dissolved in cold acidic citric acid buffer (pH 4.0-4.7).
- Distributes widely throughout the body, including crossing the blood-brain barrier and placenta.
- Undergoes chemical modification in the liver, converting into an active form that causes DNA methylation and damages pancreatic β-cells.
Cayman Chemical StreptozotocIn 50mg
A glucosamine-nitrosourea which is commonly used to induce experimental diabetes in animals; specifically targets beta cells, entering via the glucose transporter GLUT2 and causing alkylation of DNA, leading to the destruction of beta cells
Medchemexpress LLC HY-15608 100mg , MPTP (hydrochloride) CAS:23007-85-4 Purity:98%
Medchemexpress, HY-15608 100mg MPTP (hydrochloride) CAS:23007-85-4 Formula:C12H16ClN Purity:98% MPTP (hydrochloride) is a prodrug to the neurotoxin MPP + which causes permanent symptoms of Parkinson's disease. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 117467-28-4 | Medchem Express | Cefditoren (Pivoxil) | 10mg | 446268452 | HY-17452A | MFCD00933166 | 620.71 | C25H28N6O7S3
Pharmablock | 4-chloro-2-fluoro-pyridine-3-carbaldehyde | 25mg | 784546848 | PBT4959 | 1232432-20-0 | MFCD15143389 | 159.540 | C6H3ClFNO
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